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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T7587 | Tenapanor | RDX-5791,RDX 5791,AZD 1722,Tenapanor free base,RDX5791,AZD-1722,AZD1722 | Sodium Channel |
Tenapanor (RDX 5791) is an inhibitor of the sodium-proton (Na(+)/H(+)) exchanger NHE3, which plays a prominent role in sodium handling in the gastrointestinal tract and kidney. Tenapanor possesses an excellent preclinica... | |||
T6344 | Sevelamer hydrochloride | Sevelamer HCl | FXR , Autophagy |
Sevelamer hydrochloride (Sevelamer HCl) is a phosphate binding drug used to treat hyperphosphatemia via binding to dietary phosphate and prevents its absorption. | |||
T21417 | Dihydrotachysterol | Hytakerol,HSDB-3314,HSDB3314,Parterol,HSDB 3314 | |
Dihydrotachysterol (DHT) is a biologically active synthetic analog of vitamin D. It promotes intestinal absorption of active calcium and phosphate . It is also beneficial in the treatment of hypoparathyroidism. | |||
T70605 | NaPi2b Inhibitor 15 | ||
NaPi2b is primarily expressed in the small intestine, lungs, and testes and plays an important role in phosphate homeostasis. The inhibition of NaPi2b, responsible for intestinal phosphate absorption, is considered to re... | |||
T76151 | Glycerol kinase | ||
Glycerol Kinase (GyK), a bacterial sugar kinase essential for glycerol metabolism, catalyzes the transformation of glycerol into glycerol-3-phosphate (G3P), marking the metabolism's initial step. This enzyme plays a pivo... |